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Various sedation levels offer significant advantages in facilitating procedural interventions for patients undergoing medical or invasive surgical procedures. These levels span from anxiolysis to general anesthesia, providing a spectrum of sedative effects to cater to specific patient needs. Anxiolysis reduces anxiety and is achieved through minimal sedation, enabling patients to remain awake and responsive while feeling more at ease during the procedure. This level can benefit minor...
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Related Experiment Video

Updated: Sep 10, 2025

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists
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Sex-Dependent Differences in Colonoscopy Sedation: Protocol for a Scoping Review.

Niels Brink Mylin1,2, Veronica Ott1,2, Ann Merete Møller1,3

  • 1Department of Clinical Medicine, Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark.

Acta Anaesthesiologica Scandinavica
|August 26, 2025
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Summary
This summary is machine-generated.

This scoping review examines sex differences in colonoscopy sedation and their effect on colonoscopy quality indicators (CQIs). Findings will inform practice for improved patient outcomes.

Keywords:
CQIs (caecal intubation rate etc.)colonoscopysedationsex/gender

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Area of Science:

  • Gastroenterology
  • Clinical Pharmacology

Background:

  • Sedation practices in colonoscopy may differ between sexes.
  • Understanding these differences is crucial for optimizing colonoscopy quality indicators (CQIs).

Purpose of the Study:

  • To map existing evidence on sex differences in colonoscopy sedation.
  • To assess the impact of these differences on colonoscopy quality indicators.

Main Methods:

  • Adherence to Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) guidelines.
  • Comprehensive literature search across MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials.
  • Inclusion of original studies investigating sex-based differences in sedation and their influence on CQIs.

Main Results:

  • A structured overview of current evidence will be presented.
  • Data will be charted on trial characteristics, demographics, sedation, and gender-dependent outcomes.
  • A narrative summary with supplementary statistics will be provided.

Conclusions:

  • The review will highlight evidence gaps regarding sex differences in colonoscopy sedation.
  • Findings will contribute to a better understanding of factors influencing colonoscopy quality.
  • This evidence mapping is essential for refining sedation protocols and improving patient care.