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Sex-Dependent Differences in Colonoscopy Sedation: Protocol for a Scoping Review
Niels Brink Mylin1,2, Veronica Ott1,2, Ann Merete Møller1,3
1Department of Clinical Medicine, Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark.
This scoping review examines sex differences in colonoscopy sedation and their effect on colonoscopy quality indicators (CQIs). Findings will inform practice for improved patient outcomes.
Area of Science:
- Gastroenterology
- Clinical Pharmacology
Background:
- Sedation practices in colonoscopy may differ between sexes.
- Understanding these differences is crucial for optimizing colonoscopy quality indicators (CQIs).
Purpose of the Study:
- To map existing evidence on sex differences in colonoscopy sedation.
- To assess the impact of these differences on colonoscopy quality indicators.
Main Methods:
- Adherence to Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) guidelines.
- Comprehensive literature search across MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials.
- Inclusion of original studies investigating sex-based differences in sedation and their influence on CQIs.
Main Results:
- A structured overview of current evidence will be presented.
- Data will be charted on trial characteristics, demographics, sedation, and gender-dependent outcomes.
- A narrative summary with supplementary statistics will be provided.
Conclusions:
- The review will highlight evidence gaps regarding sex differences in colonoscopy sedation.
- Findings will contribute to a better understanding of factors influencing colonoscopy quality.
- This evidence mapping is essential for refining sedation protocols and improving patient care.
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