Frantz tumor with asymptomatic microscopic hematuria: Case report

Area of Science:

• Oncology
• Gastroenterology
• Surgical Pathology

Background:

• Solid pseudopapillary neoplasm (SPN) of the pancreas is a rare, low-malignancy tumor predominantly affecting young women.
• Clinical presentation is often asymptomatic or atypical, leading to incidental diagnosis via imaging.
• Optimal treatment strategies for SPN remain an area requiring further knowledge.

Purpose of the Study:

• To enhance understanding of the occurrence and clinical characteristics of pancreatic SPN.
• To investigate treatment strategies and patient outcomes for SPN.
• To report a rare case of SPN presenting with asymptomatic microscopic hematuria.

Main Methods:

• A case study of a 17-year-old female with asymptomatic microscopic hematuria and an incidentally discovered pancreatic mass.
• Diagnostic imaging included abdominal enhanced computed tomography and magnetic resonance imaging.
• Surgical intervention involved distal pancreatectomy and splenectomy, with histopathological confirmation of SPN.

Main Results:

• The patient recovered without complications following surgery and was discharged.
• Postoperative follow-up confirmed the resolution of hematuria and no tumor recurrence at 4 months.
• Histopathological analysis confirmed SPN, with imaging revealing tumor involvement of the splenic artery and compression of the left kidney.

Conclusions:

• SPN diagnosis is frequently incidental due to subtle or absent symptoms.
• Surgical resection is the established standard of care for SPN, associated with excellent patient prognosis.
• Asymptomatic microscopic hematuria is an extremely rare presentation of SPN, potentially linked to extrinsic compression of renal structures.