Reaction to Cutaneous Filler Elleva Poly-l-Lactic Acid: Report of Two Cases

Area of Science:

• Dermatology
• Pathology
• Aesthetic Medicine

Background:

• Increasing demand for aesthetic procedures necessitates understanding potential complications.
• Subcutaneous nodules are a known risk of injectable aesthetic treatments.
• Histopathology is vital for identifying the composition of dermal fillers.

Observation:

• Two cases of subcutaneous nodules following Elleva (poly-l-lactic acid) injections were analyzed.
• Detailed histopathological examination of the nodules was performed.
• Morphological characteristics of Elleva were identified in the tissue samples.

Findings:

• The histopathological analysis revealed specific features of poly-l-lactic acid filler material within the nodules.
• Distinct inflammatory and foreign body reactions were observed.
• The findings confirm Elleva as a potential cause of subcutaneous nodule formation.

Implications:

• Accurate histopathological identification of fillers like Elleva is crucial for managing adverse events.
• Understanding nodule formation mechanisms can inform future product development and injection techniques.
• This case study contributes to the literature on injectable filler complications and their diagnosis.