Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

3.2K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
3.2K
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

687
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
687
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

2.9K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.9K
Disorders of the Urinary System01:20

Disorders of the Urinary System

477
The urinary system is responsible for eliminating waste and excess fluids from the body. However, disorders of the urinary system can arise due to various reasons like infections, stress, age, congenital abnormalities, and lifestyle.
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
477
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

1.2K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
1.2K
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

540
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
540

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparing Caregivers' Perspectives on the Health-related Quality of Life of Children With Cerebral Palsy.

Journal of pediatric orthopedics·2026
Same author

Proactive Fecal Calprotectin Home Monitoring in Ulcerative Colitis: Results of a Prospective Randomized Control Trial.

Gastroenterology·2026
Same author

Enhancing access to a pediatric surgical specialty through virtual care and outreach clinics: A pilot quality improvement initiative at a tertiary children's hospital.

Journal of pediatric surgery·2026
Same author

Acute Respiratory Tract Infections and Severe Disease Among Hospitalized Children.

JAMA network open·2026
Same author

Sensitivity of gargle samples compared to swabs for SARS-CoV-2 detection with nucleic acid amplification testing: a systematic review and meta-analysis.

Virology journal·2026
Same author

A pilot randomized trial of ketamine for suicidal ideation in a pediatric emergency department.

CJEM·2026

Related Experiment Video

Updated: Sep 10, 2025

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
06:46

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

Published on: July 5, 2022

2.9K

Prevalence and Risk Factors for Bladder and Bowel Dysfunction in Children With Type 1 Diabetes.

Kristen Favel1,2, Maryellen S Kelly3,4, Shing Tat Theodore Lam5,6

  • 1Division of Pediatric Nephrology, Department of Pediatrics, University of California San Francisco, San Francisco, California, USA.

Pediatric Diabetes
|August 27, 2025
PubMed
Summary

Children with type 1 diabetes (T1D) have a higher prevalence of bowel and bladder dysfunction (BBD) compared to healthy peers. Poor glycemic control is linked to BBD, emphasizing the need for early screening and intervention in pediatric T1D management.

More Related Videos

Real-Time Void Spot Assay
06:39

Real-Time Void Spot Assay

Published on: February 10, 2023

2.1K
Video Imaging and Spatiotemporal Maps to Analyze Gastrointestinal Motility in Mice
07:41

Video Imaging and Spatiotemporal Maps to Analyze Gastrointestinal Motility in Mice

Published on: February 3, 2016

14.2K

Related Experiment Videos

Last Updated: Sep 10, 2025

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
06:46

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

Published on: July 5, 2022

2.9K
Real-Time Void Spot Assay
06:39

Real-Time Void Spot Assay

Published on: February 10, 2023

2.1K
Video Imaging and Spatiotemporal Maps to Analyze Gastrointestinal Motility in Mice
07:41

Video Imaging and Spatiotemporal Maps to Analyze Gastrointestinal Motility in Mice

Published on: February 3, 2016

14.2K

Area of Science:

  • Pediatric Endocrinology
  • Gastroenterology
  • Urology

Background:

  • Urologic complications are common in adults with type 1 diabetes (T1D).
  • Data on bowel and bladder dysfunction (BBD) in pediatric T1D is limited.
  • This study addresses the prevalence, risk factors, and impact of BBD in children with T1D.

Purpose of the Study:

  • To determine the prevalence of BBD in children with T1D versus healthy controls.
  • To identify clinical factors associated with BBD in childhood T1D.
  • To assess the bother associated with BBD symptoms in pediatric T1D.

Main Methods:

  • Cross-sectional, multicenter survey of children aged 5-16 with T1D and controls.
  • Vancouver Symptom Score (VSS) used to assess bowel and bladder symptoms.
  • BBD defined as VSS score ≥ 11; logistic regression for risk factor analysis.

Main Results:

  • BBD prevalence was 21.5% in T1D versus 10.5% in controls.
  • Poorer glycemic control correlated with higher BBD likelihood in T1D.
  • Urinary incontinence caused the most bother; male sex associated with greater symptom bother.

Conclusions:

  • Pediatric T1D is associated with a significantly higher prevalence of BBD.
  • Early identification and intervention for BBD are crucial in pediatric T1D.
  • Comprehensive T1D management, including glycemic control, is vital for mitigating BBD burden.