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Factors Influencing Chronic Pain After Hysterectomy for Uterine Fibroids: Development and Validation of a Nomogram Prediction Model

  • 0Department of Gastroenterology, Meizhou People's Hospital, Meizhou, Guangdong Province, 514011, People's Republic of China.
Journal of Pain Research +

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August 27, 2025

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August 27, 2025

View abstract on PubMed

Summary

This summary is machine-generated.

This study developed a nomogram to predict chronic pain after hysterectomy for uterine fibroids. The model accurately identifies patients at risk, aiding preoperative planning and consultation for uterine fibroid treatment.

Area Of Science

  • Gynecology
  • Surgical Oncology
  • Pain Medicine

Background

  • Hysterectomy for uterine fibroids can lead to chronic pain.
  • Predictive tools are needed to identify at-risk patients.
  • Accurate prediction aids in preoperative planning and patient counseling.

Purpose Of The Study

  • To develop and validate a nomogram prediction model for chronic pain after hysterectomy for uterine fibroids.
  • Identify independent risk factors for developing chronic pain post-surgery.
  • Assess the predictive performance and clinical utility of the nomogram.

Main Methods

  • Retrospective study of 315 patients undergoing hysterectomy for uterine fibroids.
  • Patients were divided into training (n=220) and validation (n=95) datasets.
  • Multivariate logistic regression and nomogram construction using R software.

Main Results

  • Preoperative pain, prior surgery, endometriosis, anxiety, and high Pain Catastrophic Scale (PCS) scores were significant risk factors.
  • The nomogram demonstrated high predictive performance (AUC: 0.841 training, 0.825 validation).
  • Calibration curves showed good consistency; decision curve analysis indicated clinical utility within a specific probability range.

Conclusions

  • A validated nomogram accurately predicts the risk of chronic pain following hysterectomy for uterine fibroids.
  • This tool is valuable for preoperative risk assessment and patient consultation.
  • The nomogram can improve patient management and outcomes in gynecological surgery.

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