Assessment of Visual Function Using Yellow-Tinted Filter in Patients with Pre-Perimetric and Early Open Angle...

Area of Science:

• Ophthalmology
• Visual Science

Background:

• Glaucoma, including pre-perimetric glaucoma (PPG) and primary open-angle glaucoma (POAG), affects visual function.
• Assessing visual function in early glaucoma stages is crucial for timely intervention.
• External filters may offer a non-invasive method to potentially enhance visual performance.

Purpose of the Study:

• To evaluate the impact of the KIROS 1-400 yellow-tinted filter on contrast sensitivity (CS) and visual field (VF) indices in patients with PPG and early POAG.
• To determine if the KIROS 1-400 lens can objectively improve visual function parameters in early glaucoma.

Main Methods:

• A comparative observational, within-subject study involving 30 PPG eyes and 50 POAG eyes.
• Contrast sensitivity was measured using the Pelli-Robson chart.
• Standard automated perimetry (SAP) assessed VF indices (MD, PSD, VFI, GHT) with and without the KIROS 1-400 filter.

Main Results:

• The KIROS 1-400 filter significantly improved contrast sensitivity (median logCS increase of 0.03) in both PPG and POAG groups.
• No significant changes were observed in mean deviation (MD), pattern standard deviation (PSD), or visual field index (VFI).
• The filter reduced borderline Glaucoma Hemifield Test (GHT) classifications but showed only fair agreement with unfiltered results.

Conclusions:

• The KIROS 1-400 yellow-tinted filter enhances contrast sensitivity in patients with early glaucoma (PPG and POAG).
• The filter demonstrated no significant impact on standard visual field indices.
• Caution is advised when interpreting GHT results with this filter; further studies on long-term benefits are recommended.