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Updated: Sep 10, 2025

Herbs-Partitioned Moxibustion on the Navel in a Rat Model of Primary Dysmenorrhea with Cold Coagulation and Blood Stasis
Published on: October 4, 2024
Early pubertal timing is a risk factor for adolescent dysmenorrhea
Christel M Portengen1, Tristin Smith2, Esmeralda Hidalgo-Lopez1,2
1Department of Psychology, University of Michigan, Ann Arbor, MI USA.
Early puberty, indicated by pubertal timing, is a novel risk factor for dysmenorrhea (painful periods). This finding suggests that pubertal development, not just menarche, can predict painful periods in females.
Area of Science:
- Reproductive health
- Adolescent medicine
- Puberty research
Background:
- Early menarche is linked to increased dysmenorrhea risk.
- However, other pubertal development markers precede menarche.
- Understanding these earlier markers could improve risk prediction.
Purpose of the Study:
- To investigate the association between early pubertal timing and dysmenorrhea risk.
- To identify novel markers for dysmenorrhea risk beyond menarcheal age.
Main Methods:
- Utilized data from the Adolescent Brain Cognitive Development Study®.
- Estimated pubertal timing using random effects linear growth curves.
- Included pubertal status indicators excluding menarche for postmenarcheal females.
Main Results:
- Early pubertal timing was associated with a 22-31% increased odds of dysmenorrhea.
- This association remained significant across varying dysmenorrhea severities (none, mild, severe).
Conclusions:
- Early pubertal timing is a novel and significant predictor of dysmenorrhea risk.
- Assessing pubertal development before menarche can aid in identifying at-risk females.
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