Spontaneous Internal Fistulization of a Pancreatic Pseudocyst Into the Duodenum: A Case Report

Pancreatic pseudocysts are organized fluid collections without epithelial lining, usually containing pancreatic juice or liquefied necrotic tissue. Advances in imaging techniques, particularly ultrasound and computed tomography, have significantly improved the diagnosis and management of these cystic lesions. In recent years, minimally invasive approaches such as endoscopic drainage and interventional radiology have become important therapeutic alternatives. Laparoscopic cystodigestive anastomosis is also increasingly used in selected cases. We report a rare case of spontaneous fistulization of a pancreatic pseudocyst into the duodenum. The diagnosis of such fistulization remains challenging due to its rarity and the absence of specific symptoms. This case highlights the possibility of managing spontaneous pancreatic pseudocyst fistulization using endoscopic techniques alone, without the need for surgical intervention. This minimally invasive approach emphasizes the importance of endoscopy in the management of complex pancreatic fluid collections.