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Updated: Sep 10, 2025

Sequencing of Bacterial Microflora in Peripheral Blood: our Experience with HIV-infected Patients
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Atypical Presentation of Blastocystis-Related Dysentery in an HIV-Infected Patient

Didi Candradikusuma1,2,3, Handono Kalim2, Loeki Enggar Fitri3,4

  • 1Doctoral Program in Medical Science, Department of Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, East Java, Indonesia.

International Medical Case Reports Journal
|August 27, 2025
PubMed

Insights

Blastocystis hominis (B. hominis) infection can cause severe dysentery in immunocompromised individuals. Advanced diagnostics like qPCR are crucial for timely identification and treatment of B. hominis in HIV patients.

Area of Science:

  • Medical Parasitology
  • Infectious Diseases
  • Immunocompromised Host Research

Background:

  • Blastocystis hominis is a common intestinal protozoan, often asymptomatic.
  • Severe B. hominis infections are rare, typically occurring in immunocompromised individuals.

Observation:

  • A case of severe dysentery caused by B. hominis in an HIV-seropositive patient is presented.
  • The infection presented with significant gastrointestinal distress.

Findings:

  • Microscopy and quantitative Polymerase Chain Reaction (qPCR) confirmed B. hominis infection.
  • qPCR demonstrated high sensitivity and specificity for parasite detection.

Implications:

  • This case highlights the potential for severe B. hominis manifestations in immunocompromised patients.
  • Accurate diagnosis using advanced methods like qPCR is vital for effective management.
  • Prompt treatment, including antiparasitic and antiretroviral therapy, is essential.
Keywords:
Blastocystis hominisHIVbloody diarrheaqPCR

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