Related Experiment Video
Updated: Sep 10, 2025
07:49
Measuring Local Anaphylaxis in Mice
Published on: October 14, 2014
19.5K
Cost-effective care in anaphylaxis prevention and management
Jason Sanders1, Clare Boldt2, Brinda Prasanna Kumar3
1Dartmouth Hitchcock Medical Center, Department of Pediatrics, Lebanon, New Hampshire, USA.
Summary
Fatal anaphylaxis is rare, but its burden is high. Health economic analyses show screening is low value, and individualized management considering patient preferences is key for cost-effective care.
Area of Science:
- Medical Economics
- Allergy and Immunology
Background:
- Anaphylaxis, a severe hypersensitivity reaction, poses a significant societal burden and cost, despite fatal outcomes being rare.
- Fear of anaphylaxis also contributes to the overall societal impact.
Purpose of the Study:
- To review key health-economic analyses related to anaphylaxis management.
- To inform value-based care models for anaphylaxis.
Main Methods:
- Review of existing health economic evaluations and cost-effectiveness analyses concerning anaphylaxis.
- Analysis of different management strategies, including screening, observation, and epinephrine device selection.
Main Results:
- Screening approaches for anaphylaxis prevention demonstrate low health-economic value.
- Prolonged observation of asymptomatic patients post-anaphylaxis is rarely cost-effective.
- The most cost-effective epinephrine device is accessible and affordable to the patient.
Conclusions:
- Individualized anaphylaxis management is crucial, prioritizing patient values and preferences.
- Health economic considerations support tailored treatment strategies over broad screening or prolonged observation.
- Focus on accessible and affordable epinephrine devices is essential for effective community management.
Related Concept Videos
02:06Allergic Reactions
28.6K
Overview
28.6K
01:25Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs
453
Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
453
01:30Adrenergic Agonists: Therapeutic Uses
947
Adrenergic agonists have diverse therapeutic uses across various medical conditions and emergencies.
Emergency and Intensive Care Unit (ICU) applications: Pressor agents increase blood pressure, heart rate, and contractility in shock and organ failure situations. Dopamine can induce vasodilation and stimulate adrenoceptors. Endogenous catecholamines are effective in treating cardiogenic shock. α2-agonists like clonidine can reverse anesthesia-induced hypertension.
Allergies and...
Emergency and Intensive Care Unit (ICU) applications: Pressor agents increase blood pressure, heart rate, and contractility in shock and organ failure situations. Dopamine can induce vasodilation and stimulate adrenoceptors. Endogenous catecholamines are effective in treating cardiogenic shock. α2-agonists like clonidine can reverse anesthesia-induced hypertension.
Allergies and...
947
01:30Asthma-IV: Diagnostic and Management
2.6K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
2.6K
01:17Drugs Used in Lower Respiratory Disorders: Overview
578
Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
578
01:30Asthma-IV: Nursing Management
3.3K
The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
First, in...
3.3K