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Updated: Sep 10, 2025

Human Serum Anti-aquaporin-4 Immunoglobulin G Detection by Cell-based Assay
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Distinct AQP4 Alterations in Movement Disorders with Primary Synucleinopathy

Lingbing Wang1,2, Onur Tanglay1, Feifei Su1

  • 1Brain and Mind Centre & Faculty of Medicine and Health School of Medical Sciences, The University of Sydney, Sydney, NSW, Australia.

Movement Disorders : Official Journal of the Movement Disorder Society
|August 27, 2025
PubMed
Summary

Aquaporin-4 (AQP4) changes differ in Parkinson's disease and multiple system atrophy, revealing distinct disease mechanisms. These findings highlight AQP4's role in neurodegenerative pathways.

Keywords:
Parkinson's diseasealpha‐synucleinaquaporin‐4astrocytesmultiple system atrophy

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