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The Blurred Lines Between New Psychoactive Substances and Potential Chemical Weapons
Loreto N Valenzuela-Tapia1, Cristóbal A Quintul1, Nataly D Rubio-Concha1
1Escuela de Química y Farmacia, Facultad de Ciencias, Universidad San Sebastián, Puerto Montt 5501842, Chile.
The study examines the evolution of chemical threats, from historical nerve agents to novel psychoactive substances (NPSs). It highlights the need for enhanced regulations and international cooperation to prevent hostile use of toxic chemicals.
Area of Science:
- Chemical security
- Toxicology
- International relations
Background:
- Historical use of chemical warfare agents has evolved.
- Emerging threat of new psychoactive substances (NPSs) for hostile purposes.
- Fentanyl, lysergamides, and phencyclidine pose significant risks.
Purpose of the Study:
- Analyze historical and recent cases of nerve agent and NPS misuse.
- Identify key chemical families and their characteristics.
- Assess regulatory gaps and propose preventative measures.
Main Methods:
- Narrative literature review.
- Searched specialized databases (PubMed, ScienceDirect, etc.).
- Included sources from international organizations (OPCW, UNODC).
Main Results:
- Identified main families of conventional agents (G, V, A, Novichok) and NPSs (lysergamides, PCP, fentanyl derivatives).
- Highlighted ease of synthesis and high toxicity profiles.
- Revealed regulatory gaps facilitating illicit production.
Conclusions:
- Strengthen regulatory frameworks and surveillance systems.
- Promote ethical protocols in chemical research.
- Enhance international cooperation to prevent chemical threats.
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