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Related Experiment Video

Updated: May 12, 2026

Examining Local Network Processing using Multi-contact Laminar Electrode Recording

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Published on: September 8, 2011

Protocol for investigating working memory modulation of visual signal processing in the monkey extrastriate cortex

Majid Roshanaei¹, Mohammad Reza Daliri¹, Zahra Bahmani²

¹Neuroscience & Neuroengineering Research Lab, Biomedical Engineering Department, School of Electrical Engineering, Iran University of Science and Technology (IUST), Narmak, Tehran 16846-13114, Iran.

|August 27, 2025

Summary

This study outlines a protocol to examine how working memory influences visual processing in the brain. It details methods for recording neural activity during a spatial working memory task in monkeys.

Keywords:

Behavior Cognitive Neuroscience Neuroscience

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Published on: September 8, 2011

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Area of Science:

Neuroscience
Cognitive Neuroscience
Primate Research

Background:

The extrastriate cortex is crucial for visual signal processing.
Understanding the influence of cognitive states like working memory on neural activity is vital.

Purpose of the Study:

To present a detailed protocol for investigating the impact of working memory on visual signal processing.
To establish a methodology for recording and analyzing neural data in response to visual stimuli under working memory load.

Main Methods:

A spatial working memory task was designed for monkeys.
Local field potentials (LFPs) and spiking activity were recorded from middle temporal (MT) neurons.
LFP data preprocessing and analysis using inter-trial coherence (ITC) were performed to determine visual signal arrival times.

Main Results:

The protocol enables the measurement of visual signal arrival times in the extrastriate cortex.
It allows for the investigation of how working memory modulates neural responses.

Conclusions:

This protocol provides a framework for studying the interplay between working memory and visual perception.
It facilitates future research into the neural mechanisms underlying cognitive control of sensory processing.