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A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
Identification and Stereoselective Total Synthesis of an Insect Homosesquiterpene from the Clonal Raider Ant Ooceraea
Ryan M Alam1, Yoko Nakamura1,2, Stefan Bartram1
1Department of Natural Product Biosynthesis, Max Planck Institute for Chemical Ecology, Hans-Knöll-Straße 8, D-07745 Jena, Germany.
Abstract:
Ants typically demonstrate a high level of complex social behavior that is largely mediated by chemical communication. In recent years, the Clonal raider ant Ooceraea biroi has become a promising model system for the study of social behavior in ants. Here we report the profile of extracted volatiles from O. biroi and, following detection of an α-homofarnesene as the major component, unambiguously confirm its structural identity as (3Z,6E)-14-methyl-α-farnesene through preparative stereoselective total synthesis.
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