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A High Throughput, Multiplexed and Targeted Proteomic CSF Assay to Quantify Neurodegenerative Biomarkers and Apolipoprotein E Isoforms Status
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Large-scale CSF proteome profiling identifies biomarkers for accurate diagnosis of frontotemporal dementia

Yanaika S Hok-A-Hin1, Lisa Vermunt2,3, Carel F W Peeters4

  • 1Neurochemistry Laboratory, Department of Laboratory Medicine, Amsterdam Neuroscience, VU University Medical Center, Amsterdam UMC, Amsterdam, The Netherlands. Y.hok-a-hin@amsterdamumc.nl.

Molecular Neurodegeneration
|August 27, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
BiomarkersCSFFTDFTLDProteomicsTDP43Tau

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Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
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