Diagnosis and Management of Imported Malaria in the Emergency Department

Alisa McQueen1, Jonathan Mannheim2

  • 1Associate Professor of Emergency Medicine, Rush Medical College, Attending Physician, Pediatric Emergency Medicine, John H. Stroger, Jr. Hospital of Cook County.

Pediatric Emergency Care
|August 28, 2025
PubMed

Insights

Imported malaria in children is rising globally due to migration. This review covers diagnosing and managing imported malaria in non-endemic countries, focusing on travel history, challenges, and acute care.

Area of Science:

  • Global Health
  • Pediatric Infectious Diseases
  • Travel Medicine

Background:

  • Malaria poses a significant global health burden, particularly in endemic regions like sub-Saharan Africa and parts of South/Central America.
  • Increased global migration leads to a rise in pediatric malaria cases presenting in non-endemic countries, termed imported malaria.

Purpose of the Study:

  • To review the diagnosis and management of imported malaria in children.
  • To highlight key aspects of travel history, diagnostic difficulties, and acute management strategies for imported pediatric malaria.

Main Methods:

  • Literature review focusing on imported malaria in pediatric populations.
  • Synthesis of information on clinical presentation, diagnostic approaches, and treatment protocols.

Main Results:

  • Travel history is crucial for identifying potential malaria exposure in children presenting with febrile illness in non-endemic areas.
  • Diagnostic challenges include low parasite density and non-specific symptoms, necessitating high clinical suspicion.
  • Prompt diagnosis and appropriate antimalarial treatment are vital for favorable outcomes in imported pediatric malaria.

Conclusions:

  • Imported malaria in children requires careful consideration in non-endemic settings, especially in returning travelers.
  • Effective management hinges on thorough travel history, timely diagnosis, and prompt, correct treatment.
  • Awareness and preparedness are essential for healthcare providers managing pediatric imported malaria cases.