Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Parkinson's Disease: Overview01:15

Parkinson's Disease: Overview

702
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
702
Parkinson's Disease: Treatment01:24

Parkinson's Disease: Treatment

376
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
376
Disorders of the Nervous Tissue01:28

Disorders of the Nervous Tissue

1.6K
Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
1.6K
Myasthenia Gravis: Overview and Treatment01:20

Myasthenia Gravis: Overview and Treatment

1.9K
Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
1.9K
Antiepileptic Drugs: Modulators of Neurotransmitter Release Mediated by SV2A Protein01:20

Antiepileptic Drugs: Modulators of Neurotransmitter Release Mediated by SV2A Protein

445
Antiepileptic drugs, such as levetiracetam (Keppra) and brivaracetam (Briviact), have emerged as crucial tools in managing epilepsy. These medications exert their therapeutic effects by targeting the synaptic vesicle protein SV2A, a transmembrane glycoprotein primarily found in the brain.
SV2A is a transmembrane glycoprotein located predominantly in the brain, modulating the release of neurotransmitters for neuronal communication. Both levetiracetam and brivaracetam exhibit a high affinity for...
445
Disorders of the Autonomic Nervous System01:18

Disorders of the Autonomic Nervous System

815
The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body.
Raynaud's disease, also known as Raynaud's...
815

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Hoffmann Reflex.

NeuroSci·2026
Same author

Restless Legs Syndrome: A Network Model of Iron-Dependent Neuromodulation-A Narrative Review.

Brain sciences·2026
Same author

Regulatory Variation at TERT and TERC Shows Limited Association with Early-Onset Alzheimer's Disease in Carriers of the Mexican Founder Mutation <i>PSEN1</i> A431E.

Medical sciences (Basel, Switzerland)·2026
Same author

Quantum-Inspired and Non-Classical Approaches to Consciousness: Models, Evidence and Constraints.

Brain sciences·2026
Same author

Combination therapy with pregabalin and thioctic acid offers safer pain control in diabetic neuropathy: a multicenter, double-blind, non-inferiority trial.

Brain communications·2026
Same author

L-Alliin Modulates Brain Region-Specific Neuroinflammatory Responses to Lipopolysaccharide in Diet-Induced Obese Mice.

Brain sciences·2026
Same journal

Anterior Cingulate Cortex Mediates State-Dependent Prioritization of Distressed Conspecifics.

Brain sciences·2026
Same journal

Hemispherotomy for Pediatric Post-Traumatic Epilepsy.

Brain sciences·2026
Same journal

When Robots Learn: Artificial Intelligence and the Next Human-Centered Era of Neurorehabilitation.

Brain sciences·2026
Same journal

The Association Between Changes in White Matter Microstructure and Cognitive Function in Older Adults with Mild Cognitive Impairment.

Brain sciences·2026
Same journal

Beyond Ventricular Enlargement: Multimodal MRI Assessment Improves Surgical Decision-Making in Normal Pressure Hydrocephalus.

Brain sciences·2026
Same journal

The Effects of Personalized Observation, Execution, and Mental Imagery (POEM) Therapy in Logopenic Primary Progressive Aphasia: A Telepractice-Based Single-Case Study.

Brain sciences·2026
See all related articles

Related Experiment Video

Updated: Sep 10, 2025

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
05:54

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor

Published on: December 13, 2017

14.1K

Tremor: Clinical Frameworks, Network Dysfunction and Therapeutics.

Emmanuel Ortega-Robles1, Oscar Arias-Carrión1,2

  • 1División de Neurociencias, Clínica, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra, Mexico City 14389, Mexico.

Brain Sciences
|August 28, 2025
PubMed
Summary
This summary is machine-generated.

Tremor diagnosis is complex due to varied causes. Recent advances in diagnostics, including AI and neuroimaging, are improving accuracy for conditions like essential tremor and parkinsonian tremor.

Keywords:
AI in movement disordersessential tremornetwork oscillationsneuromodulationtremor classification

More Related Videos

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

15.4K
Low-cost Protocol of Footprint Analysis and Hanging Box Test for Mice Applied the Chronic Restraint Stress
06:38

Low-cost Protocol of Footprint Analysis and Hanging Box Test for Mice Applied the Chronic Restraint Stress

Published on: January 23, 2019

19.0K

Related Experiment Videos

Last Updated: Sep 10, 2025

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
05:54

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor

Published on: December 13, 2017

14.1K
Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

15.4K
Low-cost Protocol of Footprint Analysis and Hanging Box Test for Mice Applied the Chronic Restraint Stress
06:38

Low-cost Protocol of Footprint Analysis and Hanging Box Test for Mice Applied the Chronic Restraint Stress

Published on: January 23, 2019

19.0K

Area of Science:

  • Neurology
  • Movement Disorders
  • Clinical Neuroscience

Background:

  • Tremor is a prevalent yet diagnostically challenging movement disorder.
  • Clinical heterogeneity and overlapping etiologies complicate tremor diagnosis.
  • The 2018 consensus redefined tremor syndromes with a two-axis classification, introducing new categories like essential tremor plus.

Purpose of the Study:

  • To synthesize recent advances in tremor epidemiology, classification, pathophysiology, and treatment.
  • To provide an integrated, clinically relevant framework aligned with emerging diagnostic and therapeutic paradigms.
  • To address the diagnostic challenges posed by tremor's clinical heterogeneity.

Main Methods:

  • Review of recent advances in tremor research.
  • Synthesis of information on epidemiology, classification, pathophysiology, and treatment.
  • Examination of specific tremor syndromes (essential tremor, parkinsonian tremor, etc.) through syndromic, etiological, and mechanistic lenses.

Main Results:

  • Electrophysiology, neuroimaging, wearable sensors, and artificial intelligence are enhancing diagnostic precision for tremors.
  • Current rating scales have limitations, but emerging biomarkers show promise.
  • Various tremor syndromes are analyzed, highlighting diagnostic and mechanistic insights.

Conclusions:

  • Pathophysiologically grounded diagnostic criteria are increasingly crucial as treatments evolve toward neuromodulation and precision medicine.
  • Integrating network-based frameworks, digital diagnostics, and individualized treatment strategies is key to advancing tremor care.