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Related Concept Videos

Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

39
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
39

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Updated: Sep 10, 2025

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
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Borderline Oxacillin-Resistant Staphylococcus aureus (BORSA) Bacteremia-Case Report.

Beverly Buffart1, Philippe Clevenbergh2, Alina Stiuliuc3

  • 1Department of Microbiology, Laboratoire Hospitalier Universitaire de Bruxelles-Universitair Laboratorium Brussel (LHUB-ULB), Université Libre de Bruxelles (ULB), 1000 Brussels, Belgium.

Antibiotics (Basel, Switzerland)
|August 28, 2025
PubMed
Summary

Borderline oxacillin-resistant Staphylococcus aureus (BORSA) infections are rare and difficult to detect. This case highlights challenges in diagnosing and treating BORSA bacteremia, emphasizing the need for improved methods.

Keywords:
BORSAStaphylococcus aureusbacteremiamethicillin resistance

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Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Clinical Diagnostics

Background:

  • Borderline oxacillin-resistant Staphylococcus aureus (BORSA) is a rare phenotype.
  • Detection of BORSA is challenging for clinical laboratories.
  • Optimal treatment strategies for BORSA infections are not well-established.

Observation:

  • A patient with systemic lupus erythematosus developed BORSA bacteremia.
  • Antimicrobial susceptibility testing showed conflicting results for oxacillin.
  • The patient experienced a delay in appropriate management due to diagnostic challenges.

Findings:

  • A rare case of BORSA bacteremia was identified.
  • The infection was successfully treated with linezolid and ciprofloxacin.
  • Diagnostic discrepancies complicated the initial management.

Implications:

  • Improved diagnostic methods for BORSA are needed.
  • Further research on BORSA treatment is crucial.
  • Clinical awareness of BORSA is essential for timely intervention.