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PRACT-India: Practical Recommendations on Acne Care and Medical Treatment in India-A Modified Delphi Consensus
Nina Madnani1, Abir Saraswat2, Anand Nott3
1Department of Dermatology, Sir PD Hinduja Hospital and Medical Research Centre, Mumbai 400016, India.
Antibiotics (Basel, Switzerland)
|August 28, 2025
Summary
This consensus provides evidence-based acne vulgaris treatment guidelines for India. It emphasizes topical retinoids as first-line therapy and combination treatments to improve efficacy and combat antibiotic resistance.
Area of Science:
- Dermatology
- Evidence-based medicine
- Clinical guidelines
Background:
- Acne vulgaris is common, but India lacks specific management guidelines.
- Effective acne treatment requires more than just medication, including skincare and patient education.
- Tailored recommendations are needed for India's diverse population.
Purpose of the Study:
- To develop region-specific, evidence-based recommendations for acne vulgaris management in India.
- To optimize acne treatment strategies considering Indian patient factors.
- To provide practical guidance for healthcare professionals.
Main Methods:
- A panel of 14 experienced dermatology experts participated.
- A modified Delphi process with two virtual voting rounds was employed.
- 61 statements across seven clinical domains were evaluated for consensus (≥75% agreement).
Main Results:
- Topical retinoids are recommended as first-line acne treatment.
- Combination therapies (e.g., benzoyl peroxide, topical antibiotics) are preferred to boost efficacy and reduce resistance.
- Hormonal therapies are suggested for resistant acne in females, with safety considerations for pregnancy and lactation.
Conclusions:
- This expert consensus offers practical, evidence-based acne management strategies for India.
- Recommendations integrate pharmacological and non-pharmacological approaches for individualized care.
- The guidance promotes antibiotic stewardship and improved patient adherence for better outcomes.
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