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Artificial Intelligence and Its Role in Predicting Periprosthetic Joint Infections
Diana Elena Vulpe1,2, Catalin Anghel3, Cristian Scheau1,4
1The "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Biomedicines
|August 28, 2025
Summary
Artificial intelligence (AI) shows promise in improving early diagnosis of periprosthetic joint infections (PJIs) after joint replacement. This review explores AI
Area of Science:
- Orthopedic surgery
- Medical informatics
- Artificial intelligence in healthcare
Background:
- Periprosthetic joint infections (PJIs) are a major complication of total joint replacement, impacting patient quality of life and healthcare expenses.
- Early and accurate PJI diagnosis is crucial but challenging with traditional methods.
- Artificial intelligence (AI) offers advanced data analysis capabilities for healthcare applications.
Purpose of the Study:
- To review the current applications of AI in predicting PJIs.
- To explore the types of AI algorithms used and their performance.
- To identify limitations and challenges in implementing AI for PJI diagnosis.
Main Methods:
- Literature review of studies utilizing AI for PJI prediction.
- Analysis of AI algorithm types and reported performance metrics.
- Discussion of clinical implementation challenges.
Main Results:
- AI algorithms demonstrate potential for enhancing the assessment of risk factors and prediction of complications like PJIs.
- Various AI algorithms are being explored, with performance metrics varying across studies.
- Significant challenges and limitations exist for widespread clinical adoption.
Conclusions:
- AI holds promise for improving early PJI detection and management.
- Further research and validation are needed to overcome implementation barriers.
- AI integration could lead to more efficient and accurate PJI diagnostics.
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