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Predictors of Incisional Hernia After Cytoreductive Surgery and HIPEC: A Retrospective Analysis
Daniela Di Pietrantonio1, Fabrizio D'Acapito1, Massimo Framarini1
1General and Oncologic Surgery, Morgagni-Pierantoni Hospital, AUSL Romagna, 47121 ForlìItaly, Italy.
Medicina (Kaunas, Lithuania)
|August 28, 2025
Summary
Incisional hernias are common after cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). Hypertension is a key risk factor, but surgical details were not significant predictors.
Area of Science:
- Oncology
- Surgical Oncology
- Abdominal Surgery
Background:
- Incisional hernia is a frequent complication post-cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC).
- Identifying risk factors is crucial for preventing this complication.
Purpose of the Study:
- To determine patient and surgical factors predicting incisional hernia development after CRS and HIPEC.
- To inform targeted preventive strategies for high-risk individuals.
Main Methods:
- Retrospective analysis of 122 patients who underwent CRS and HIPEC.
- Logistic regression models were employed to identify significant predictors of incisional hernia.
Main Results:
- The incidence of incisional hernia was 23.8%.
- Hypertension emerged as an independent risk factor for incisional hernia.
- Peritoneal Cancer Index (PCI), operative duration, and abdominal closure technique did not show significant association.
Conclusions:
- Preoperative identification of patients at higher risk for incisional hernia is possible.
- Preventive measures like prophylactic mesh placement and vigilant postoperative monitoring should be considered for at-risk patients.
