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Published on: December 23, 2022
Predictors of Incisional Hernia After Cytoreductive Surgery and HIPEC: A Retrospective Analysis
Daniela Di Pietrantonio1, Fabrizio D'Acapito1, Massimo Framarini1
1General and Oncologic Surgery, Morgagni-Pierantoni Hospital, AUSL Romagna, 47121 ForlìItaly, Italy.
Insights
Incisional hernias are common after cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). Hypertension is a key risk factor, but surgical details were not significant predictors.
Area of Science:
- Oncology
- Surgical Oncology
- Abdominal Surgery
Background:
- Incisional hernia is a frequent complication post-cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC).
- Identifying risk factors is crucial for preventing this complication.
Purpose of the Study:
- To determine patient and surgical factors predicting incisional hernia development after CRS and HIPEC.
- To inform targeted preventive strategies for high-risk individuals.
Main Methods:
- Retrospective analysis of 122 patients who underwent CRS and HIPEC.
- Logistic regression models were employed to identify significant predictors of incisional hernia.
Main Results:
- The incidence of incisional hernia was 23.8%.
- Hypertension emerged as an independent risk factor for incisional hernia.
- Peritoneal Cancer Index (PCI), operative duration, and abdominal closure technique did not show significant association.
Conclusions:
- Preoperative identification of patients at higher risk for incisional hernia is possible.
- Preventive measures like prophylactic mesh placement and vigilant postoperative monitoring should be considered for at-risk patients.
Abstract:
Background and Objectives: Incisional hernia is a common complication following cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). This study aimed to identify patient and surgical factors associated with its occurrence. Materials and Methods: We conducted a retrospective analysis of 122 patients undergoing CRS and HIPEC. Logistic regression models were applied to identify predictors of incisional hernia development. Results: Incisional hernia occurred in 23.8% of patients. Hypertension was identified as an independent factor associated with increased risk. Peritoneal Cancer Index (PCI), operative time, and abdominal wall closure technique were not found to be significantly associated with hernia development. Conclusions: Preoperative identification of high-risk patients may support the adoption of targeted preventive strategies, including prophylactic mesh placement and enhanced postoperative surveillance.
