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Updated: Sep 9, 2025

Live Imaging to Study Microtubule Dynamic Instability in Taxane-resistant Breast Cancers
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Recent Advances in Microtubule Targeting Agents for Cancer Therapy

Henrique C Assunção1,2, Patrícia M A Silva3,4,5, Hassan Bousbaa5

  • 1Laboratory of Organic and Pharmaceutical Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Rua de Jorge de Viterbo Ferreira, 288, 4050-313 Porto, Portugal.

Molecules (Basel, Switzerland)
|August 28, 2025
PubMed
Summary

Researchers are discovering new microtubule-targeting agents (MTAs) to overcome cancer resistance and toxicity. This review focuses on advancements since 2020, emphasizing structure-activity relationship studies for more effective anticancer drugs.

Keywords:
cancermicrotubule-targeting agentsnatural productsstructure-activity relationship studies

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