Related Experiment Video
Updated: May 5, 2026
07:30
Transcanalicular Diode Laser-assisted Dacryocystorhinostomy for the Treatment of Primary Acquired Nasolacrimal Duct Obstruction
Published on: October 13, 2017
11.1K
Clinicopathologic Features, Surgical Treatment, and Pathological Characterization of Canine Dacryops with Different
Barbara Lamagna1, Luigi Navas1, Francesco Prisco2
1Unit of Surgery, Department of Veterinary Medicine and Animal Productions, University of Naples "Federico II", 80137 Naples, Italy.
Veterinary Sciences
|August 28, 2025
Summary
This study details two unusual canine lacrimal gland cyst (dacryops) cases in brachycephalic dogs, revealing non-myoepithelial cells beneath the cyst lining. Findings suggest dacryops pathogenesis in dogs may not involve neuromuscular dysfunction.
Area of Science:
- Veterinary ophthalmology
- Pathology
- Immunohistochemistry
Background:
- Lacrimal cysts (dacryops) are uncommon in dogs with unclear pathogenesis.
- This report details clinicopathologic and immunohistochemical features of two unusual dacryops cases in brachycephalic dogs.
Observation:
- Two brachycephalic dogs (Cane Corso and French Bulldog) presented with lacrimal cysts.
- Clinical signs included swelling, blepharospasm, epiphora, entropion, and corneal ulceration.
- Histopathology revealed cystic structures with cuboidal epithelia and rare goblet cells.
Findings:
- Immunohistochemistry showed Cytokeratin-positive epithelium and smooth muscle actin (SMA)-positive cells beneath the epithelium.
- Double-color immunofluorescence indicated these SMA-positive cells lacked p63 expression, suggesting a non-myoepithelial phenotype.
- Canine dacryops findings contrast with some human dacryops studies.
Implications:
- The presence of non-myoepithelial cells challenges previous theories on dacryops pathogenesis.
- Findings suggest canine dacryops pathogenesis should exclude failure of ductular neuromuscular contractility.
- This research contributes to understanding canine lacrimal system disorders.
Related Concept Videos
01:30Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
434
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
434
01:28Acute Pyelonephritis II: Diagnostic Studies and Management
842
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
842
01:26Differential Staining Technique
2.7K
Differential staining is an essential microbiological technique that exploits variations in cell wall structures to classify and identify microorganisms. It facilitates the distinction of bacteria, aiding in diagnostic and research applications. Two of the most widely used differential staining methods are Gram staining and acid-fast staining, both of which rely on the chemical and structural differences in bacterial cell walls.Gram Staining TechniqueGram staining differentiates bacteria by...
2.7K
01:13Special Staining Techniques
1.7K
Specialized staining techniques play a vital role in microbiology by enabling the visualization of specific bacterial structures that remain undetectable with standard microscopy methods. These techniques not only enhance the structural visualization of bacterial cells but also provide critical insights into their pathogenicity and classification. Additionally, they support diagnostic and research endeavors in microbiology by identifying key bacterial features.Capsule Staining for Virulence...
1.7K
01:28Methods of Classification and Identification
2.3K
Bacterial identification relies on a diverse array of techniques to classify and understand microorganisms, each tailored to uncover specific characteristics. Traditional morphological approaches, while still valuable, are limited for closely related or structurally simple organisms. Modern methods integrate biochemical, serological, genetic, and advanced molecular tools to achieve greater accuracy.Morphological and Biochemical TechniquesMorphological characteristics, such as cell shape and...
2.3K
01:14Atypical Pneumonia
84
Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease...
84