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Clinical Presentation and Management of Atypical Meningioma in a Five-Year-Old Child: A Case Report
Mohammed Bentourqi1, Mohamed Moukhlissi1, Meriem Bouabid1
1Radiation Oncology, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR.
Abstract:
While meningiomas are the most frequent among adult primary intracranial tumors, they remain a rare condition in children, accounting for less than 5% of pediatric central nervous system tumors. These tumors have been linked to conditions like neurofibromatosis type 2 and radiation exposure, and they usually present with increased intracranial pressure and other neurological symptoms. Diagnosis relies on magnetic resonance imaging (MRI), which reveals heterogeneous masses often mistaken for other types of tumors. Surgical resection is the first line of treatment; however, it is often complicated by anatomical characteristics and the fast growth rate of pediatric meningiomas. Adjuvant radiotherapy is commonly used in high-grade or residual meningiomas. Histopathological evaluation is essential to determine the grade and subtype of the meningioma, which in turn influences the prognosis and clinical management. The case involves a five-year-old boy suffering from a large atypical meningioma, managed successfully by complete surgical resection followed by radiotherapy. This scenario underscores the significance of integrated therapeutic modalities that bring together surgery and radiotherapy for better long-term control over the disease in children with meningioma cases.
Insights
Pediatric meningiomas are rare brain tumors. Successful management of a pediatric atypical meningioma involved surgical resection and radiotherapy, highlighting the importance of combined treatments for better outcomes.
Area of Science:
- Pediatric neuro-oncology
- Neurosurgery
- Radiation oncology
Background:
- Meningiomas are rare in children, comprising <5% of pediatric central nervous system tumors.
- Associated with neurofibromatosis type 2 and radiation exposure.
- Typically present with increased intracranial pressure and neurological deficits.
Observation:
- Diagnosis via MRI reveals heterogeneous masses, often misdiagnosed.
- Surgical resection is primary treatment but challenging due to tumor characteristics.
- Adjuvant radiotherapy is used for high-grade or residual tumors.
Findings:
- Histopathological evaluation is crucial for grading and subtyping.
- A 5-year-old boy with atypical meningioma achieved successful outcomes.
- Complete surgical resection followed by radiotherapy was the chosen management.
Implications:
- Integrated therapeutic approaches combining surgery and radiotherapy are vital.
- This strategy offers improved long-term disease control in pediatric meningioma cases.
- Highlights the need for tailored treatment protocols for pediatric brain tumors.
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