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Related Concept Videos

Bone Disorders01:29

Bone Disorders

3.9K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
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Essential Minerals for Bone Health01:31

Essential Minerals for Bone Health

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The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
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Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

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The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
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Bone Remodeling01:40

Bone Remodeling

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Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
38.5K
Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

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Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
3.2K
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

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The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
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Estrogen-Like Effect of Bazi Bushen Capsule in Ovariectomized Rats
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Exercise Behavior to Prevent Osteoporosis.

Sahar Mohammadnabizadeh, Maryam Mohammadi

    Nursing Research
    |August 28, 2025
    PubMed
    Summary

    Women

    Area of Science:

    • Health behavior research
    • Osteoporosis prevention strategies
    • Social Cognitive Theory applications

    Background:

    • Exercise is crucial for osteoporosis prevention, yet women's participation is insufficient.
    • Suboptimal physical activity levels in women pose a public health concern for bone health.

    Purpose of the Study:

    • To evaluate Health Belief Model constructs and self-regulation in relation to exercise for osteoporosis prevention.
    • To identify psychological factors influencing exercise behavior in premenopausal women.

    Main Methods:

    • Cross-sectional survey of 250 premenopausal women (ages 30-49).
    • Utilized questionnaires assessing health beliefs, self-regulation, awareness, and exercise behavior.

    Main Results:

    Keywords:
    exercisehealth behaviorosteoporosis

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    • Exercise behavior scores were generally low among participants.
    • Perceived benefits, susceptibility, self-efficacy, motivation, self-regulation, and barriers significantly predicted exercise behavior.

    Conclusions:

    • Perceived benefits and self-efficacy are key predictors of exercise behavior for osteoporosis prevention.
    • Enhancing self-efficacy and educating on benefits are vital for successful health promotion in middle-aged women.