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Updated: Sep 9, 2025

Analysis of Electrocardiograms and Behavior in Mice from Pregnancy to Lactation Period
Published on: April 5, 2024
Association between wearable sensor signals and expected hormonal changes in pregnancy.
Giulia Milan1, Lauren Ariniello2, Katie Baca-Motes3
1Scripps Research Translational Institute, 3344 N Torrey Pines Ct Plaza Level, La Jolla, CA, 92037, USA; University of California San Diego, La Jolla, CA, 92037, USA.
Wearable sensors effectively track pregnancy changes, correlating with hormonal shifts. This technology may enable early risk assessment for adverse pregnancy outcomes.
Area of Science:
- Biomedical Engineering
- Maternal Health
- Digital Health
Background:
- The US faces a maternal health crisis, requiring innovative pregnancy monitoring.
- Wearable sensors offer a potential solution for tracking physiological and behavioral changes during pregnancy.
Purpose of the Study:
- To assess wearable sensor efficacy in monitoring pregnancy
- To examine associations between sensor data and hormonal fluctuations
Main Methods:
- Longitudinal cohort study using a mobile research platform.
- Collected data from 99 participants using wearable devices (Apple, Garmin, Fitbit).
- Analyzed resting heart rate, physical activity, and sleep patterns.
Main Results:
- Resting heart rate showed distinct patterns throughout pregnancy and postpartum.
- Sleep patterns changed significantly during pregnancy.
- Strong correlation (R²=0.93) found between RHR fluctuations and hormonal changes.
Conclusions:
- Wearable sensors non-invasively monitor pregnancy changes aligned with hormonal shifts.
- Potential for early risk assessment of adverse pregnancy outcomes.
- Feasible to capture physiological signals in pregnancies with adverse outcomes.
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