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Related Concept Videos

Brain Imaging01:14

Brain Imaging

310
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
310

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Related Experiment Video

Updated: Sep 9, 2025

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Multifunctional bioelectronics for brain-body circuits.

Atharva Sahasrabudhe1,2,3, Claudia Cea1,2,3, Polina Anikeeva1,2,3,4,5

  • 1K. Lisa Yang Brain-Body Center, Massachusetts Institute of Technology.

Nature Reviews Bioengineering
|August 29, 2025
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Summary
This summary is machine-generated.

New implantable neurotechnologies are crucial for studying brain-body communication, essential for homeostasis and cognitive functions. These advanced devices enable long-term monitoring of organ-brain signaling pathways.

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Area of Science:

  • Neuroscience
  • Bioengineering
  • Physiology

Background:

  • The brain constantly processes internal organ signals via neural, endocrine, and immune pathways, maintaining homeostasis.
  • This intricate brain-body cross-talk significantly impacts cognitive functions and neurological disorders.
  • Understanding these pathways is vital, yet challenging to study during behavior.

Purpose of the Study:

  • To review advancements in multifunctional implantable neurotechnologies.
  • To highlight technologies enabling causal studies of organ-brain circuits during behavior.
  • To discuss strategies for robust bioelectronic interfaces for long-term brain-body signaling research.

Main Methods:

  • Review of recent developments in implantable neurotechnology.
  • Discussion of material selection and device architectures.
  • Analysis of integration, power, and data transfer for bioelectronic interfaces.

Main Results:

  • Development of multifunctional implantable neurotechnologies is progressing.
  • Challenges in electrical, optical, and chemical interrogation of organ-brain circuits are being addressed.
  • Approaches for robust bioelectronic interfaces are being established.

Conclusions:

  • Multifunctional implantable neurotechnologies are essential for studying brain-body signaling.
  • These technologies facilitate causal investigations of organ-brain circuits during behavior.
  • Advancements are paving the way for long-term studies of physiological homeostasis and neurological function.