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Related Concept Videos

Anastomoses01:19

Anastomoses

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In human anatomy, anastomosis refers to a connection or opening between two things, particularly between blood vessels or other tubular structures. The term is derived from the Greek term 'anastomosis,' which means 'outlet' or 'opening.' This natural network of connections plays a critical role in the survival and functionality of the human body.
Anastomoses can be formed at arterial, venous, and lymphatic vessels.
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The Aorta01:14

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The aorta is the largest artery in the human body. It originates from the left ventricle of the heart and extends down to the abdomen, where it splits into two smaller arteries. Structurally, it can be divided into four main parts: the ascending aorta, the aortic arch, the thoracic aorta, and the abdominal aorta.
The average diameter of the aorta is approximately 2-3 cm, but the size can vary depending on the section of the aorta and the individual's age, sex, and body size. The aorta is...
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The Arch of Aorta01:10

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The coronary arteries, originating from the ascending aorta, bifurcate from two sinuses located within the ascending aorta. Positioned just above the aortic semilunar valve, these sinuses house essential aortic baroreceptors and chemoreceptors, crucial for maintaining cardiac function. The left coronary artery and the right coronary artery branch off from the left posterior and anterior aortic sinuses, respectively.
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Thoracic Aorta01:15

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The thoracic section of the aorta begins at the T5 vertebra and extends to the T12 level at the diaphragm, initially progressing through the mediastinum to the left of the spinal column. Throughout its course in the thoracic segment, the thoracic aorta emits various offshoots known collectively as visceral and parietal branches. The branches that predominantly supply blood to visceral organs are termed visceral branches and include bronchial, pericardial, esophageal, and mediastinal arteries,...
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Abdominal Aorta01:25

Abdominal Aorta

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Once the aorta traverses the diaphragmatic plane at the aortic hiatus, it is known as the abdominal aorta. This anatomical structure is positioned leftward of the spinal column, encased within a cocoon of adipose tissue behind the peritoneal cavity. It terminates at the L4 vertebra, where it splits into the common iliac arteries. Prior to this bifurcation, the abdominal aorta gives rise to several vital branches.
The celiac trunk, a singular artery, divides into the left gastric artery, which...
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Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

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Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
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Updated: May 6, 2026

The In ovo CAM-assay as a Xenograft Model for Sarcoma
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Primary Jejunal Angiosarcoma.

Michelle Mai1, Sapana Gupta2, Kanhai Farrakhan2

  • 1Warren Alpert Medical School of Brown University, Providence, RI.

ACG Case Reports Journal
|August 29, 2025
PubMed
Summary
This summary is machine-generated.

Primary jejunal angiosarcoma is a rare cancer. Early diagnosis and surgery did not prevent metastasis, suggesting a need for earlier systemic therapy in localized cases.

Keywords:
jejunal angiosarcomasmall bowel angiosarcoma

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Area of Science:

  • Oncology
  • Gastroenterology
  • Soft-tissue neoplasm research

Background:

  • Primary jejunal angiosarcoma is a rare, aggressive soft-tissue neoplasm with a poor prognosis.
  • Diagnosis typically involves endoscopic intervention, radiographic imaging, and immunohistochemistry.
  • Limited cases (62) reported, with most presenting with distant metastases.

Observation:

  • A 51-year-old male presented with melena and a jejunal mass.
  • Initial staging revealed angiosarcoma without metastases.
  • Diagnosis confirmed via histomorphology and immunohistochemistry.

Findings:

  • Despite early staging and successful surgical resection, the patient developed metastatic disease 6 months post-surgery.
  • This case underscores the aggressive nature of jejunal angiosarcoma.

Implications:

  • Highlights the need for comprehensive diagnostic strategies in small bowel tumors.
  • Suggests considering earlier systemic or neoadjuvant therapy for early-stage jejunal angiosarcoma.
  • Emphasizes the potential for aggressive behavior even in localized disease.