Nonsteroidal Anti-Inflammatory Drug-Induced Granulomatous Colitis: A Case Report and Literature Review of a Vanishing Colonic Mass Mimicking Malignancy
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Updated: Apr 9, 2026

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
Published on: August 26, 2014
Joel Gabin Konlack Mekontso1, Akil Olliverrie1, Nitin Pendyala1
1Department of Internal Medicine, New York City Health and Hospitals South Brooklyn Health, Brooklyn, New York, USA.
Abstract:
This case report describes a rare occurrence of nonsteroidal anti-inflammatory drugs (NSAID)-induced focal colonic granulomatous mass mimicking a malignant colonic mass. It highlights the diagnostic challenges of NSAID-related gastrointestinal complications and stresses the importance of considering such causes in similar presentations. Prompt recognition and withdrawal of the offending NSAID can prevent unnecessary surgical intervention and facilitate symptom resolution. This case underscores the value of a detailed medication history and cautious NSAID use to reduce the risk of adverse gastrointestinal effects.
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