Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Kidney Transplant I: Introduction

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...

Kidney Transplant II: Surgical Procedure

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...

Acute Kidney Injury III: Clinical Manifestations

Acute Kidney Injury III: Clinical Manifestations

Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Machine Learning Prediction of Pediatric In-Hospital Survival Before Extracorporeal Membrane Oxygenation Cannulation.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026

Same author

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS.

Annals of clinical and translational neurology·2026

Same author

Impact of Selumetinib on Long-Term Pain Medication Utilization in Pediatric Patients: A Retrospective US Claims Database Study.

Pain and therapy·2026

Same author

Recombinant Human Bone Morphogenetic Protein-2 (rhBMP-2) as an Alternative to Autologous Bone Graft in Pediatric Craniofacial Reconstruction: A Systematic Review.

Annals of plastic surgery·2026

Same author

Systolic propulsion of the eyeballs in severe tricuspid regurgitation: a case series and review of the literature.

Open medicine (Warsaw, Poland)·2026

Same author

Enhanced three-dimensional navigation with intraoperative positioning system in coil embolization of complex aneurysm.

Journal of vascular surgery cases and innovative techniques·2026

Search research articles

Related Experiment Video

Updated: Sep 9, 2025

Thermal Ablation for the Treatment of Abdominal Tumors

Thermal Ablation for the Treatment of Abdominal Tumors

Published on: March 7, 2011

Kidney function decline in cT1a patients treated with Microwave Ablation versus Partial Nephrectomy.

Jessica Qiu¹, Guofen Yan², Aisha Kazeem³

¹University of Virginia School of Medicine, 1340 Jefferson Park Ave, Charlottesville, VA 22903.

Kidney Cancer Journal : Official Journal of the Kidney Cancer Association

|August 29, 2025

Summary

Partial nephrectomy (PN) and microwave ablation (MWA) show similar kidney function decline for small renal masses. Baseline kidney function, not treatment type, significantly impacts outcomes after these procedures.

Keywords:

ablation techniques chronic kidney disease chronic renal insufficiencies kidney function microwave ablation partial nephrectomy renal cell carcinoma small renal masses

More Related Videos

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

Application of Laparoscopic Hepatectomy Combined with Intraoperative Microwave Ablation in Colorectal Cancer Liver Metastasis

Application of Laparoscopic Hepatectomy Combined with Intraoperative Microwave Ablation in Colorectal Cancer Liver Metastasis

Published on: March 3, 2023

Related Experiment Videos

Last Updated: Sep 9, 2025

Thermal Ablation for the Treatment of Abdominal Tumors

Thermal Ablation for the Treatment of Abdominal Tumors

Published on: March 7, 2011

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

Application of Laparoscopic Hepatectomy Combined with Intraoperative Microwave Ablation in Colorectal Cancer Liver Metastasis

Application of Laparoscopic Hepatectomy Combined with Intraoperative Microwave Ablation in Colorectal Cancer Liver Metastasis

Published on: March 3, 2023

Area of Science:

Nephrology
Urology
Oncology

Background:

Microwave ablation (MWA) is an emerging treatment for small renal masses (SRM), with oncological outcomes comparable to partial nephrectomy (PN).
Further research is needed to understand the comparative impact of MWA and PN on kidney function decline in patients with clinical T1a (cT1a) SRM.

Purpose of the Study:

To compare the progression of kidney function decline in patients with cT1a SRM treated with either MWA or PN.
To analyze differences in estimated glomerular filtration rate (eGFR) changes, chronic kidney disease (CKD) upstaging, and composite endpoints between the two treatment groups.

Main Methods:

Prospective data from 2015-2021 were analyzed, with kidney function data collected through 2024 from a single institution.
Kidney function decline was assessed by a 30% drop in eGFR, CKD upstaging, and a composite endpoint, using Cox proportional hazards models.

Main Results:

The study included 97 MWA and 49 PN patients. MWA patients were older with lower baseline eGFR and higher pre-treatment CKD rates.
Univariate analysis showed no significant association between treatment modality and kidney function decline endpoints.
After adjusting for patient factors, only baseline eGFR remained significantly associated with kidney function decline.

Conclusions:

No statistically significant difference in kidney function decline was observed between PN and MWA for cT1a SRM.
Adjusting for patient characteristics attenuated the initial observed higher hazard for MWA, highlighting the importance of baseline factors.