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Updated: Sep 9, 2025

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Almost Nobody Is Using ChatGPT to Write Academic Science Papers (Yet)
Heather Desaire1, Madeline Isom1, David Hua1
1Department of Chemistry, University of Kansas, Lawrence, KS 66045, USA.
Abstract:
We assessed 19,000 scientific introductions to measure the level of undisclosed use of ChatGPT in scientific papers published in 2023 and early 2024. We applied a "stylistics" approach that has previously been shown to be effective at differentiating AI-generated text from human-written text in a variety of venues. Ten different MDPI journals were selected for this study, and the rate of use of undisclosed AI writing in these journals was fairly consistent across the journals. We estimate that ChatGPT was used for writing or significant editing in about 1 to 3% of the introductions tested. This analysis is the first systematic study of detecting undisclosed ChatGPT in published manuscripts in cases where obvious indicators, such as phrases like "regenerate response", are not present. The work demonstrates that generative AI is not polluting mainstream journals to any appreciable extent and that the overwhelming majority of scientists remain hesitant to embrace this tool for late-stage writing and editing.
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