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Real time video-based gaze tracking for detecting subtle deviation angle change in abducens nerve palsy
Natalia Christina Angsana1, Amelia Devy Indriasari1, Indra Tri Mahayana1
1Department of Ophthalmology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Jl. Farmako, Sekip Utara, Yogyakarta 55248, Indonesia.
International Journal of Ophthalmology
|August 29, 2025
Summary
A real-time gaze tracking system accurately measured visual angles in abducens nerve palsy patients. This technology aids in diagnosing slight deviations, showing significant improvements after treatment.
Area of Science:
- Ophthalmology
- Neuroscience
- Biomedical Engineering
Background:
- Abducens nerve palsy can cause visual disturbances.
- Accurate measurement of visual angle is crucial for diagnosis and management.
- Existing methods may have limitations in real-time assessment.
Purpose of the Study:
- To evaluate a real-time video-based gaze tracking system for measuring visual angles in patients with abducens nerve palsy.
- To compare visual angle measurements between patients with abducens nerve palsy and healthy individuals.
- To assess the system's utility in detecting changes in visual angle post-treatment.
Main Methods:
- A cross-sectional study involving 39 subjects with abducens nerve palsy and 39 healthy controls.
- Utilized the GENICULA system (Gaze Tracking Artificial Intelligence for Ocular Motor Palsy), a webcam-based eye tracker.
- Employed Mann-Whitney and Wilcoxon tests for statistical analysis.
Main Results:
- The mean visual angle was significantly different between the abducens nerve palsy group (20.88±3.76) and the normal group (23.10±2.91) (P=0.011).
- The GENICULA system demonstrated a statistically significant improvement in visual angle post-treatment for abducens nerve palsy patients (P=0.039).
- The system proved easy to use, efficient, and accurate in detecting subtle visual angle changes.
Conclusions:
- The real-time video-based gaze tracking system (GENICULA) is a practical tool for assessing visual angles.
- This technology is valuable for diagnosing slight deviations in abducens nerve palsy.
- The system facilitates objective measurement and monitoring of treatment efficacy.

