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Splenic hamartoma mimicking angiosarcoma: A case report.
Su-Bin Song1, Byeong Gwan Noh2, Myeong Hun Oh1
1Department of Surgery, Pusan National University School of Medicine, Biomedical Research Institute, Pusan National University Hospital, Busan 49241, South Korea.
World Journal of Clinical Cases
|August 29, 2025
Summary
A rare splenic hamartoma mimicked angiosarcoma on imaging, emphasizing the need for careful differential diagnosis in splenic tumor management. This case highlights diagnostic challenges in rare splenic lesions.
Area of Science:
- Gastroenterology and Hepatology
- Radiology
- Pathology
Background:
- Primary splenic lesions are uncommon and often asymptomatic, posing diagnostic challenges.
- Distinguishing benign splenic hamartomas from malignant angiosarcomas can be difficult due to overlapping imaging features.
Observation:
- A 33-year-old male presented with hematemesis and epigastric pain, found to have splenomegaly and a large splenic lesion.
- Imaging suggested angiosarcoma with hepatic metastases, but histopathology confirmed a splenic hamartoma.
Findings:
- Splenic hamartoma was confirmed after splenectomy, despite preoperative imaging suspicion of angiosarcoma.
- Associated chronic inflammation was noted in the liver biopsy.
Implications:
- This case underscores the critical role of differential diagnosis in managing splenic tumors.
- Rare presentations of splenic hamartoma necessitate thorough histopathological evaluation to avoid misdiagnosis.
