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Peritoneal Dialysis-Related Peritonitis Caused by Staphylococcus caprae: A Case Report

Mayu Iwata1, Kenta Torigoe1, Sayaka Honda1

  • 1Department of Nephrology, Nagasaki University Hospital, Nagasaki, JPN.

Cureus
|August 29, 2025
PubMed

Insights

A rare case of peritoneal dialysis peritonitis caused by Staphylococcus caprae was successfully treated. Intraperitoneal vancomycin effectively resolved the infection, indicating a favorable prognosis for this Staphylococcus caprae peritonitis.

Area of Science:

  • Nephrology
  • Infectious Diseases
  • Microbiology

Background:

  • Peritoneal dialysis (PD) is a vital treatment for end-stage renal disease.
  • PD-related peritonitis is a common complication, often caused by Staphylococcus species.
  • Prompt diagnosis and effective antibiotic treatment are crucial for successful outcomes.

Observation:

  • An 88-year-old male PD patient presented with classic symptoms of peritonitis: cloudy dialysate and elevated white blood cell count.
  • Initial treatment with cefazolin and ceftazidime showed partial improvement.
  • Effluent culture identified methicillin-resistant Staphylococcus caprae as the causative agent.

Findings:

  • Switching to intraperitoneal vancomycin led to rapid resolution of peritonitis, with normalized dialysate parameters within 5 days.
  • The patient recovered fully without the need for PD catheter removal.
  • Staphylococcus caprae peritonitis, though rare, appears to be effectively managed with vancomycin.

Implications:

  • This case highlights Staphylococcus caprae as a potential pathogen in PD-related peritonitis.
  • Intraperitoneal vancomycin is an effective treatment option for S. caprae peritonitis.
  • Patients with S. caprae peritonitis may have a favorable prognosis with appropriate antibiotic therapy.
Keywords:
antibiotic therapyend-stage renal disease (esrd)peritoneal dialysisperitonitisstaphylococcus caprae

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