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Updated: Aug 14, 2026

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
Published on: April 12, 2017
Renal Leiomyosarcoma With Regional Lymph Node Metastasis and Biopsy Tract Seeding: A Case Report
Nassar M Alqurashi1, Ibrahim M Salman1, Ahmed K Yamani1
1Urology, Alhada Armed Forces Hospital, Al Hada, SAU.
Abstract:
Renal leiomyosarcoma is a rare and aggressive tumor that comprises a very small proportion of adult kidney malignancies. Its clinical and imaging characteristics can closely resemble those of other high-grade renal tumors, which complicates the diagnostic process. We report the case of a 66-year-old male patient who presented with a large left renal mass and was diagnosed with high-grade pleomorphic leiomyosarcoma. He underwent radical nephrectomy along with en bloc removal of a para-aortic lymph node, which was histologically confirmed to contain metastatic disease. In an unusual postoperative development, the patient presented with a subcutaneous mass at the prior biopsy site. This was confirmed to be tumor seeding along the biopsy tract, an infrequent occurrence in renal sarcomas.
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