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Updated: Sep 9, 2025

Murine Corneal Transplantation: A Model to Study the Most Common Form of Solid Organ Transplantation
Published on: November 17, 2014
Changes regarding solid organ transplantation during the COVID-19 pandemic
Hayrunnisa Bekis Bozkurt1, Öner Özdemir2
1Department of Pediatrics, Division of Allergy and Immunology, Ümraniye Research and Training Hospital, İstanbul 34400, Türkiye.
Abstract:
Coronavirus disease 2019 is caused by severe acute respiratory syndrome coronavirus 2 and emerged in Wuhan, China. It affects millions of people all over the world and has caused the deaths of thousands of people. Mortality rates were higher in transplant recipients and patients awaiting transplantation due to social and psychological issues. It also affected candidates who would be transplant providers and caused the transplant chain to be broken worldwide. The coronavirus disease 2019 pandemic has significantly affected solid organ transplantation procedures and led to various changes in protocols and practices to ensure patient safety and increase transplant success. These include challenges in screening protocols, prioritization of cases, telemedicine and virtual consultations, modified surgical procedures, immunosuppression management, updated research and guidelines, post-transplantation process and difficulties to control side effects, difficulties in organ procurement, and patient education/support. It requires a multidisciplinary approach, close collaboration between transplant teams, and adherence to strict infection control measures to ensure the safety of both transplant recipients and healthcare providers. In this article, we compiled the most important points in an overview of this process.
Insights
The COVID-19 pandemic significantly impacted solid organ transplantation, increasing mortality in recipients and disrupting the transplant chain. Adapting protocols and ensuring patient safety became paramount for transplant success.
Area of Science:
- Infectious Diseases
- Transplant Surgery
- Public Health
Background:
- Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, emerged in Wuhan, China.
- The pandemic led to increased mortality in transplant recipients and disrupted global organ transplantation.
- Social and psychological factors exacerbated risks for transplant candidates and providers.
Purpose of the Study:
- To provide an overview of the significant effects of the COVID-19 pandemic on solid organ transplantation.
- To highlight the challenges and necessary adaptations in transplant protocols and practices.
- To emphasize the need for a multidisciplinary approach in managing transplant procedures during the pandemic.
Main Methods:
- Review of challenges in screening, prioritization, and surgical procedures.
- Analysis of changes in telemedicine, immunosuppression management, and post-transplantation care.
- Examination of difficulties in organ procurement and patient support.
Main Results:
- Transplant procedures faced numerous challenges, including modified screening, virtual consultations, and altered surgical approaches.
- Management of immunosuppression, organ procurement, and patient education required significant adjustments.
- The pandemic necessitated strict infection control measures and close collaboration among transplant teams.
Conclusions:
- The COVID-19 pandemic profoundly impacted solid organ transplantation, necessitating adaptive strategies for patient safety and transplant success.
- Effective management requires a multidisciplinary approach, robust infection control, and continuous adaptation of protocols.
- Ensuring the safety of both transplant recipients and healthcare providers remains a critical priority.
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