Imatinib For Treatment of Multifocal Maxillofacial Giant Cell Lesions: A Case Series
Aparna B Bhat1, Jesse T Han2, Mark A Egbert3
1Oral and Maxillofacial Surgery, University of Washington.
Journal of Pediatric Hematology/Oncology
|August 29, 2025
Abstract:
Maxillofacial giant cell lesions (MGCLs) can lead to disfigurement and functional impairments. Management often involves a combination of operative and nonoperative strategies. This case series presents the first reported use of imatinib for multifocal MGCLs in a patient with Noonan syndrome, alongside 2 patients with cherubism.


