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Related Concept Videos

Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

1.7K
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
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Pulmonary Tuberculosis II01:28

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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
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Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
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Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

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Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
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Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

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Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
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Atypical Pneumonia01:14

Atypical Pneumonia

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Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease...
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The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
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The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

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[Miliary tuberculosis in the elderly: Case report].

María Alejandra Zambrano Gustin1, Marta Fernández Esteban1, Wendy Fuentes Ramos1

  • 1Servicio de Geriatría y Cuidados Paliativos. Consorci Sanitari Integral. Hospital General de Hospitalet, L'Hospitalet de Llobregat, Barcelona, España.

Revista Espanola De Geriatria Y Gerontologia
|August 29, 2025
PubMed
Summary
This summary is machine-generated.

Elderly tuberculosis presents with vague symptoms, delaying diagnosis and treatment. This case highlights nonspecific signs and drug-induced liver injury in a 90-year-old man with miliary tuberculosis.

Keywords:
Adulto mayorElderlyGeriatricsGeriatríaMiliarMiliaryTuberculosis

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Area of Science:

  • Geriatrics
  • Infectious Diseases
  • Pulmonology

Background:

  • Tuberculosis (TB) diagnosis in the elderly is often delayed due to nonspecific symptoms.
  • This leads to underdiagnosis and treatment delays, increasing morbidity and mortality.

Observation:

  • A 90-year-old male presented with asthenia, anorexia, weight loss, and leg edema.
  • Imaging revealed a diffuse bilateral reticulonodular pattern, deep vein thrombosis, and mediastinal lymphadenopathy.
  • Pulmonary CT angiography showed a cavitated infiltrate and bilateral micronodular pattern, highly suggestive of miliary tuberculosis.

Findings:

  • Tuberculosis PCR cultures confirmed the diagnosis after 72 hours.
  • The patient developed jaundice and elevated liver enzymes, indicating hepatotoxicity from anti-TB drugs.

Implications:

  • Nonspecific symptoms in the elderly can mask serious infections like miliary tuberculosis.
  • Close monitoring for drug-induced hepatotoxicity is crucial during tuberculosis treatment in elderly patients.