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Tunable spontaneous release of a carboxylic acid via a β-eliminative cleavable linker

Brenno Masina1, Nicola R F Knowles2, Ronald T Raines1

  • 1Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Bioorganic & Medicinal Chemistry Letters
|August 29, 2025
PubMed

Keywords:
Carboxylic acidDrug deliveryEsterSelf-immolative linkerβ-Elimination

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