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Updated: Sep 9, 2025

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
Published on: June 23, 2023
National, regional, and global statistics on alcohol consumption and associated burden of disease 2000-20: a
Kevin Shield1, Ari Franklin2, Ashley Wettlaufer2
1Institute for Mental Health Policy Research, Centre for Addiction and Mental Health, Toronto, ON, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada; Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Background:
Data on alcohol consumption and associated health harms are essential to evaluate progress in achieving global health goals. This study aims to estimate global alcohol consumption from 2000 to 2020, and the global burden of alcohol-attributable harms from 2000 to 2019.
Methods:
In this global analysis, adult per capita consumption data estimates were modelled on the basis of sales, survey, and traveller data. Drinking status and past 30-day heavy episodic drinking were estimated through regression analyses of 540 surveys from 174 countries. Alcohol-attributable harms were estimated using a comparative risk assessment methodology by combining alcohol consumption data with corresponding relative risks obtained from meta-analyses and cohort studies. Mortality and morbidity data were obtained from WHO Global Health Estimates.
Findings:
Globally, average alcohol consumption in 2019 among adults was 5·5 L (95% uncertainty interval 4·9-6·2), which increased from 5·1 L (4·6-5·7) in 2000. From 2019 to 2020 alcohol consumption decreased to 4·9 L (4·3-5·6). In 2019, alcohol consumption was associated with 2·6 (2·3-3·1) million deaths (4·7% of all deaths) and 116·0 million disability-adjusted life-years (DALYs) lost (4·6% of all DALYs lost). In contrast to alcohol consumption, the number of alcohol-attributable deaths decreased by 31·0% and DALYs lost per 100 000 people decreased by 27·4% from 2000 to 2019.
Interpretation:
Alcohol is attributed to a large burden of disease, which disproportionately affects people in Eastern Europe and in Central and Southern Sub-Saharan Africa, and young people. Accordingly, these regions should implement policies such as alcohol taxation increases, availability reductions, and marketing restrictions to reduce alcohol-related harms.
Funding:
WHO.
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