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Updated: Sep 9, 2025

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Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
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Transjugular Access for Left Atrial Appendage Closure
Ahmed Hussein1, Ariana Ehsan2, Adriana Olivares2
1Interventional Cardiology, Tucson Medical Center, Tucson, Arizona, USA.
JACC. Case Reports
|August 29, 2025
Summary
Transjugular left atrial appendage closure (LAAC) offers a viable alternative for patients with challenging venous anatomy unsuitable for standard transfemoral access. This approach successfully prevented stroke in high-risk atrial fibrillation patients.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Devices
Background:
- Percutaneous left atrial appendage closure (LAAC) is a key stroke prevention strategy for atrial fibrillation patients.
- Transfemoral access is the standard route for LAAC.
- Certain anatomical limitations can preclude transfemoral access.
Observation:
- Two patients with atrial fibrillation and contraindications to anticoagulation presented with venous anatomy precluding transfemoral LAAC.
- Right internal jugular venous access was utilized for trans-septal puncture in both cases.
- Specialized steerable sheaths and wire techniques facilitated optimal trajectory for device implantation.
Findings:
- Successful implantation of the Watchman FLX Pro device was achieved in both patients via the transjugular route.
- No periprocedural complications were observed.
- Follow-up imaging confirmed stable device position and effective left atrial appendage seal.
Implications:
- The transjugular approach is a technically feasible alternative for LAAC when transfemoral access is not possible.
- This method can lead to successful outcomes in anatomically challenging cases with appropriate technique and equipment.
- Expands treatment options for stroke prevention in complex atrial fibrillation patients.
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