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Updated: Sep 9, 2025

Quantification of the Potential Impact of Glyphosate-Based Products on Microbiomes
Published on: January 10, 2022
Why internists should be concerned about glyphosate
Agostino Di Ciaula1,2, Harshitha Shanmugam3, Mohamad Khalil3
1Clinica Medica "A. Murri", Department of Precision and Regenerative Medicine and Ionian Area (DiMePre-J), University of Bari "Aldo Moro" Medical School, Bari, Italy. agodiciaula@gmail.com.
Glyphosate, a common herbicide, poses significant public health risks, including noncommunicable diseases and cancer. Internal medicine experts must raise awareness and advocate for reducing exposure to this environmental hazard.
Area of Science:
- Environmental Health
- Toxicology
- Internal Medicine
Background:
- Growing evidence links environmental factors like air pollution, endocrine-disrupting chemicals, and climate change to adverse health outcomes.
- Glyphosate, a widely used herbicide, is increasingly recognized as a significant public health concern.
- Human exposure to glyphosate is associated with various health issues, including increased mortality and chronic diseases.
Purpose of the Study:
- To highlight the ethical obligation of internal medicine experts regarding environmental health.
- To underscore the risks associated with glyphosate exposure, particularly noncommunicable diseases and cancer.
- To advocate for increased awareness and action among healthcare professionals and the community.
Main Methods:
- Review of existing scientific evidence on glyphosate's health effects.
- Analysis of associations between glyphosate detection in humans and health outcomes.
- Examination of animal studies on long-term glyphosate intake and cancer incidence.
- Ethical considerations for medical professionals in addressing environmental hazards.
Main Results:
- Glyphosate exposure is linked to all-cause mortality, frailty, insulin resistance, diabetes, cardiovascular diseases, fatty liver, and COPD.
- Animal studies show a dose-dependent increase in cancer incidence with long-term glyphosate consumption, even at low levels.
- Internal medicine experts have a crucial role in educating the public and advocating for risk reduction.
Conclusions:
- Glyphosate represents a substantial environmental health risk requiring urgent attention from medical professionals.
- Ethical involvement of internists can drive discussions and actions to mitigate glyphosate-related health risks.
- A One Health approach is essential for addressing the complex interplay between environmental factors and human health.
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