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Why internists should be concerned about glyphosate.

Agostino Di Ciaula1,2, Harshitha Shanmugam3, Mohamad Khalil3

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Glyphosate, a common herbicide, poses significant public health risks, including noncommunicable diseases and cancer. Internal medicine experts must raise awareness and advocate for reducing exposure to this environmental hazard.

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Area of Science:

  • Environmental Health
  • Toxicology
  • Internal Medicine

Background:

  • Growing evidence links environmental factors like air pollution, endocrine-disrupting chemicals, and climate change to adverse health outcomes.
  • Glyphosate, a widely used herbicide, is increasingly recognized as a significant public health concern.
  • Human exposure to glyphosate is associated with various health issues, including increased mortality and chronic diseases.

Purpose of the Study:

  • To highlight the ethical obligation of internal medicine experts regarding environmental health.
  • To underscore the risks associated with glyphosate exposure, particularly noncommunicable diseases and cancer.
  • To advocate for increased awareness and action among healthcare professionals and the community.

Main Methods:

  • Review of existing scientific evidence on glyphosate's health effects.
  • Analysis of associations between glyphosate detection in humans and health outcomes.
  • Examination of animal studies on long-term glyphosate intake and cancer incidence.
  • Ethical considerations for medical professionals in addressing environmental hazards.

Main Results:

  • Glyphosate exposure is linked to all-cause mortality, frailty, insulin resistance, diabetes, cardiovascular diseases, fatty liver, and COPD.
  • Animal studies show a dose-dependent increase in cancer incidence with long-term glyphosate consumption, even at low levels.
  • Internal medicine experts have a crucial role in educating the public and advocating for risk reduction.

Conclusions:

  • Glyphosate represents a substantial environmental health risk requiring urgent attention from medical professionals.
  • Ethical involvement of internists can drive discussions and actions to mitigate glyphosate-related health risks.
  • A One Health approach is essential for addressing the complex interplay between environmental factors and human health.