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Updated: Sep 9, 2025

Identification of Post-translational Modifications of Plant Protein Complexes
Published on: February 22, 2014
Guanylate-binding proteins: emerging critical functions in plant development, immunity and stress response
Lucie Fernandez-Lochu1, Martine Lemaire-Chamley1, Christian Chevalier1
1INRAE, Université de Bordeaux, UMR1332 Biologie du Fruit et Pathologie, Villenave d'Ornon, F-33140, France.
None:
Guanylate-binding proteins (GBPs) are large GTPases that belong to the Dynamin Superfamily Protein family. In humans, GBPs are well-characterized interferon-induced GTPases, playing a central role in cell-autonomous innate immunity against infections, inflammation and cancer. GBPs orthologs have been identified in plants only recently. Despite the limited number of reports describing their functional characterization, plant GBPs share common structural and biological features, as well as functions, with animal GBPs. This review aimed at highlighting the recent knowledge acquired on the critical role of GBPs and the associated mechanisms in plant developmental processes and in plant immunity to biotic aggressions through the control of gene expression.
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