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Anti-B-cell CAR-T therapy in multiple sclerosis is simply a more profound immunoablation? No

Alessandro Bruno1, Raffaella Greco1

  • 1Hematology and Bone Marrow Transplantation Unit, IRCCS Ospedale San Raffaele, Milano, Italy.

Multiple Sclerosis (Houndmills, Basingstoke, England)
|August 30, 2025
PubMed
Abstract

No abstract available in PubMed .

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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