Related Experiment Video
Updated: Apr 11, 2026

Orthotopic Hind Limb Transplantation in the Mouse
Published on: February 12, 2016
Orthoplastic approach to limb salvage surgery in oncology: types of flaps and surgical timing
Michela Saracco1, Maria Grazia Cerrone2, Gianmarco Vavalle2
1University of Naples "Federico II", Naples, Italy.
Abstract:
Extremities are a very common site for the development of malignant tumors. A multidisciplinary approach is essential for the proper management of extremity tumors, ensuring complete surgical resection with clear margins, proper management of tissue loss, and optimal functional recovery following reconstruction. Up to 95% of patients undergo successful limb-sparing treatments, avoiding amputation. We will discuss the advantages and disadvantages of using various flaps to reconstruct upper and lower extremities. We will also explore the applications of microvascular surgery and free flaps in this context and conclude with a reflection on the timing of reconstructions.

