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The rose spots of typhoid fever: The story behind the eponym
Leonard J Hoenig1, Uwe Wollina2, Cynthia M Magro3
1Private Practice, Pembroke Pines, Florida, USA.
Abstract:
The eponym rose spots is a clinical feature of typhoid fever, first introduced in 1829 by the noted French physician Pierre Charles Alexandre Louis (1787-1872) in a landmark treatise on the disease. Pierre Louis's work paved the way for a better understanding of typhoid fever as a disease distinct from other febrile illnesses. This contribution tells the story behind the rose spot eponym, including its etymology, historic background, and clinical features. It also pays tribute to the man who coined the term, Pierre Charles Alexandre Louis.
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