Delayed breakfast in type 2 diabetes: Critical gaps and translation barriers

We respond to the article "Modifying the timing of breakfast improves postprandial glycaemia in people with type 2 diabetes: A randomised controlled trial" by Bravo-Garcia et al. While the study introduces an intriguing strategy for postprandial glycemic control, several methodological modification and detailed reporting could be done. Key variables such as participants' sleep-wake timing, daily schedules, and evening routines, which influence glucose metabolism, could be reported. Limited details on medication timing and exercise standardization could be taken care of. Additionally, cultural and socioeconomic factors, particularly in developing countries like India, challenge the practicality of delayed breakfast protocols. The physiological implications of fasting, including the Somogyi effect, warrant further exploration. These highlight the need for more comprehensive studies addressing individual, cultural, and socioeconomic factors to enhance the translational potential of breakfast timing interventions for glycemic control.